Crystal structure of Leishmania donovani glucose 6-phosphate dehydrogenase reveals a unique N-terminal domain

Isabell Berneburg; Stefan Rahlfs; Katja Becker; Karin Fritz-Wolf

doi:10.1038/s42003-022-04307-7

Communications Biology (Dec 2022)

Crystal structure of Leishmania donovani glucose 6-phosphate dehydrogenase reveals a unique N-terminal domain

Isabell Berneburg,
Stefan Rahlfs,
Katja Becker,
Karin Fritz-Wolf

Affiliations

Isabell Berneburg: Biochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University
Stefan Rahlfs: Biochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University
Katja Becker: Biochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University
Karin Fritz-Wolf: Biochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University

DOI: https://doi.org/10.1038/s42003-022-04307-7
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 14

Abstract

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Crystallographic and biochemical characterization of Leishmania donovani Glucose 6-Phosphate Dehydrogenase (LdG6PD) containing the complete N-terminal domain reveal its role in LdG6PD tetramerization and substrate binding.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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