Mixed adenoneuroendocrine carcinoma of the gallbladder, histopathological features

Abstract

An unusual case of mixed adenoneuroendocrine carcinoma is described which posed a diagnostic challenge in view of neuroendocrine component mimicking signet ring cells of adenocarcinoma. Diagnostic criteria for these mixed tumors, their histogenesis and treatment modalities are highlighted.

Keywords

• Gallbladder
• goblet cells
• mixed adenoneuroendocrine carcinoma