Identification of a germline F692L drug resistance variant in cis with Flt3-internal tandem duplication in knock-in mice
Oliver M. Dovey,
Bin Chen,
Annalisa Mupo,
Mathias Friedrich,
Carolyn S. Grove,
Jonathan L. Cooper,
Benjamin Lee,
Ignacio Varela,
Yue Huang,
George S. Vassiliou
Affiliations
Oliver M. Dovey
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
Bin Chen
Department of Medical Genetics, School of Basic Medicine, Peking Union Medical College, Beijing, China;State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China;Department of Haematology, Cambridge University Hospitals NHS Trust, UK
Annalisa Mupo
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
Mathias Friedrich
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
Carolyn S. Grove
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK;School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, Australia;PathWest Division of Clinical Pathology, Queen Elizabeth II Medical Centre, Nedlands, Australia
Jonathan L. Cooper
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
Benjamin Lee
Takeda Pharmaceuticals International, Cambridge, MA, USA
Ignacio Varela
Instituto de Biomedicina y Biotecnología de Cantabria, Santander, Spain
Yue Huang
Department of Medical Genetics, School of Basic Medicine, Peking Union Medical College, Beijing, China;State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China
George S. Vassiliou
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK;Department of Haematology, Cambridge University Hospitals NHS Trust, UK
