The Role of Albumin and Hemoglobin as Predictors of 28-day Mortality in Elderly Sepsis Patients in Mohammad Hoesin Hospital Palembang

Abstract

Introduction. Sepsis is defined as organ dysfunction caused by dysregulation of the host's response to infection. The majority of sepsis are experienced by elderly patients with high mortality rates. In the condition of sepsis, there are various body mechanisms that cause a decrease in albumin and hemoglobin. This study is to determine the predictive value of albumin and hemoglobin levels on 28-day mortality of elderly sepsis patients. Methods. Survival analysis with prospective cohort design was conducted among elderly patients diagnosed with sepsis in RSMH Palembang from July 2018-March 2019. The patient was examined for albumin and hemoglobin, and 28 days of observation were observed to see the patient alive or dead. Results. Of 21 subjects, 13 people died before 28 days, and 8 people lived until day 28. Albumin and hemoglobin <12 could not be a predictor of 28-day mortality in elderly sepsis patients (HR 0.5 95% CI 0.13-1.80, p = 0.28; HR 2.0, 95% CI 0.64-6.15, p = 0.23). Conclusion. Albumin and hemoglobin cannot be a predictor of mortality in elderly sepsis patients in Mohammad Hoesin Hospital Palembang.

Keywords

• albumin
• elderly
• hemoglobin
• mortality
• sepsis