Nature Communications (Jan 2025)

One-year mortality and re-admission rate by disease etiology in National Heart Failure Registry of India

  • Sivadasanpillai Harikrishnan,
  • Ajay Bahl,
  • Ambuj Roy,
  • Animesh Mishra,
  • Jayesh Prajapati,
  • CN Manjunath,
  • Rishi Sethi,
  • Santanu Guha,
  • Santhosh Satheesh,
  • RS Dhaliwal,
  • Meenakshi Sharma,
  • Sanjay Ganapathy,
  • Panniyammakal Jeemon

DOI
https://doi.org/10.1038/s41467-024-55362-z
Journal volume & issue
Vol. 16, no. 1
pp. 1 – 7

Abstract

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Abstract Survival outcomes of patients with heart failure (HF) based on their disease etiology are not well described. Here, we provide one-year mortality outcomes of 10850 patients with HF (mean age = 59.9 years, 31% women) in India. Ischemic heart disease (71.9%), dilated cardiomyopathy (17.3), rheumatic heart disease (5.4), non-rheumatic valvular heart disease (1.9), hypertrophic cardiomyopathy (0.8), congenital heart disease (0.7), peri-partum cardiomyopathy (0.5), restrictive cardiomyopathy (0.4), and infective endocarditis (0.1) were the main disease etiologies. Mortality rate per 100-person years of follow-up varied from 13.8 (95% CI: 6.2–30.7) in peri-partum cardiomyopathy to 92.9 (46.5–185.9) in infective endocarditis. Compared to ischemic heart disease, the mortality was two to five times higher in rheumatic heart disease (HR = 2.0; 95% CI: 1.6–2.4), congenital heart disease (2.9; 1.9–4.2), and infective endocarditis (4.8; 2.4–9.8). The wide variations in mortality rate in HF patients may bring possible clinical applicability of risk stratification.