Nature Communications (Aug 2017)

Myosin efflux promotes cell elongation to coordinate chromosome segregation with cell cleavage

  • Emilie Montembault,
  • Marie-Charlotte Claverie,
  • Lou Bouit,
  • Cedric Landmann,
  • James Jenkins,
  • Anna Tsankova,
  • Clemens Cabernard,
  • Anne Royou

DOI
https://doi.org/10.1038/s41467-017-00337-6
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 15

Abstract

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Chromatid segregation must be coordinated with cytokinesis to preserve genomic stability. Here the authors show that cells clear trailing chromatids from the cleavage site in a two-step cell elongation and demonstrate the role of myosin efflux in the second phase.