Assessing the Potential of <i>Aconitum Laeve</i> Extract for Biogenic Silver and Gold Nanoparticle Synthesis and Their Biological and Catalytic Applications

Shahbaz Ahmad; Qianqian Xu; Muhammad Tariq; Meijie Song; Chao Liu; Hai Yan

doi:10.3390/molecules29112640

Molecules (Jun 2024)

Assessing the Potential of <i>Aconitum Laeve</i> Extract for Biogenic Silver and Gold Nanoparticle Synthesis and Their Biological and Catalytic Applications

Shahbaz Ahmad,
Qianqian Xu,
Muhammad Tariq,
Meijie Song,
Chao Liu,
Hai Yan

Affiliations

Shahbaz Ahmad: School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China
Qianqian Xu: School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China
Muhammad Tariq: State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China
Meijie Song: School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China
Chao Liu: School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China
Hai Yan: School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China

DOI: https://doi.org/10.3390/molecules29112640
Journal volume & issue: Vol. 29, no. 11
p. 2640

Abstract

Read online

The adoption of green chemistry protocols in nanoparticle (NP) synthesis has exhibited substantial potential and is presently a central focus in research for generating versatile NPs applicable across a broad spectrum of applications. In this scientific contribution, we, for the first time, examined the ability of Aconitum Laeve (A. Laeve) crude extract to synthesize silver and gold nanoparticles (AgNPs@AL; AuNP@AL) and explored their potential applications in biological activities and the catalytic degradation of environmental pollutants. The synthesized NPs exhibited a distinctive surface plasmon resonance pattern, a spherical morphology with approximate sizes of 5–10 nm (TEM imaging), a crystalline architecture (XRD analysis), and potential functional groups identified by FTIR spectroscopy. The antibacterial activity was demonstrated by inhibition zones that measured 16 and 14 mm for the AgNPs@AL and AuNP@AL at a concentration of 80 µg/mL against Staphylococcus aureus and 14 and 12 mm against Escherichia coli, respectively. The antioxidant potential of the synthesized NPs was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-Oxide (PTIO), and 3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assays. Our findings suggest that the AuNP@AL effectively countered the tested radicals considerably, displaying IC50 values of 115.9, 103.54, and 180.85 µg/mL against DPPH, PTIO, and ABTS, respectively. In contrast, the AgNPs@AL showed IC50 values of 144.9, 116.36, and 95.39 µg/mL against the respective radicals. In addition, both the NPs presented significant effectiveness in the photocatalytic degradation of methylene blue and rhodamine B. The overall observations indicate that A. Laeve possesses a robust capability to synthesize spherical nanoparticles, exhibiting excellent dispersion and showcasing potential applications in both biological activities and environmental remediation.

Published in Molecules

ISSN: 1420-3049 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/molecules

About the journal

Abstract

Keywords