Peculiarities of Invasive Diarrhea in Сhildren at the Modern Stage

Abstract

In the infectious boxed department of intestinal infections in regional children’s clinical hospital (Chernivtsi), there were examined 109 children who suffered from acute intestinal infection, caused by obligate pathogenic flora, in particular, 76 patients with salmonellosis and 33 children who were diagnosed with shigellosis. The main etiological factors of salmonellosis were S.typhimurium and S.enteritidis in incidence ratio 3 : 2, shigellosis — Sh.sonnei and Sh.flexneri in the ratio 9 : 1. The average age of children with salmonellosis was 3.7 ± 0.5 years, of patients with shigellosis — 7.1 ± 0.7 years. In modern conditions, the course of salmonellosis in children is characterized by typical symptoms of bacterial lesions of the gastrointestinal tract with the development of local gastrointestinal form of the disease (gastroenterokolitis variant in 57.9 % of cases), mainly, moderate (86.9 %). In 89.2 % of patients, the onset of the disease was accompanied by the fever reaction (febrile values in 57.9 % of children) and manifestations of gastrointestinal dysfunction as the diarrhea (77.6 %) and emetic (57.9 %) syndromes. In the vast majority of children with shigellosis, a disease proceeds in colitis form (75.8 %) of moderate severity (90.9 %) with significant cytoscopic signs of distal colon inflammation. Laboratory hematology indices in both groups were characterized by insignificant leukocytosis with significant regenerative shift and the tendency to anemia in children with salmonellosis.

Keywords

• children
• salmonellosis
• shigellosis
• clinical picture