Oman Medical Journal (Nov 2021)

Disseminated Cryptosporidiosis in an Infant with Non-HIV Pediatric Immunodeficiency: First Case Report from Oman

  • Tariq AL Farsi,
  • Sanjeewani Weerakoon,
  • Jalila Mohsin,
  • Hussein Al Mashayakhi,
  • Khawater Ahmed,
  • Amal Al Maani,
  • Khuloud Aboqusida,
  • Nashat Al Sukaiti

DOI
https://doi.org/10.5001/omj.2021.44
Journal volume & issue
Vol. 36, no. 6
pp. e326 – e326

Abstract

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Cryptosporidium is a rare but important pathogen, especially in children with immunodeficiency. Intestinal cryptosporidiosis is well described in immunocompetent and immunocompromised children, but respiratory and disseminated cryptosporidiosis in immunodeficient children is not often reported. We describe an Omani infant with disseminated cryptosporidiosis and failing pharmacological therapy in the context of severe combined immunodeficiency. Chronic diarrhea can be an initial symptom of immunodeficiency in the pediatric population. Awareness of cryptosporidiosis is critical to early detection and management for such patients. As antiparasitic agents are often ineffective, amelioration of immunosuppression in immunodeficient children should be a priority.

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