AIDS Research and Therapy (Apr 2005)

Clade, Country and Region-specific HIV-1 Vaccines: Are they necessary?

  • Zirkel Amy,
  • Jones Bart G,
  • Surman Sherri,
  • Zhan Xiaoyan,
  • Stambas John,
  • Brown Scott A,
  • Coleclough Chris,
  • Slobod Karen S,
  • Freiden Pamela J,
  • Brown Brita,
  • Sealy Robert,
  • Bonsignori Mattia,
  • Hurwitz Julia L

DOI
https://doi.org/10.1186/1742-6405-2-3
Journal volume & issue
Vol. 2, no. 1
p. 3

Abstract

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Abstract Today, scientists are often encouraged to custom-design vaccines based on a particular country or clade. Here, we review the scientific literature and then suggest that the overwhelming endeavor to produce a unique vaccine for every world region or virus subtype may not be necessary.