Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission

Abstract

Introduction Degenerative changes in the otolithic organs have been theorized to be caused by the mechanical obstruction to endolymphatic flow, possibly resulting in endolymphatic hydrops (ELH). Otolin-1 is an otoconial matrix protein that crosses the blood labyrinth barrier and has been found in the serum of healthy and diseased patients.

Keywords

• Meniere disease
• otolithic membrane
• endolymph drainage
• biomarkers