Hypervirulent Klebsiella pneumoniae infection in a woman with a CDH1 gene mutation
Alexander J. Kaye,
Adam T. Chin,
Michelle C. Liang,
Roberto Viau Colindres
Affiliations
Alexander J. Kaye
Tufts University School of Medicine, Boston, MA, USA; Corresponding author. Present address: Rutgers New Jersey Medical School, University Hospital, Newark, NJ, USA.
Adam T. Chin
New England Eye Center, Tufts Medical Center, Boston, MA, USA
Michelle C. Liang
New England Eye Center, Tufts Medical Center, Boston, MA, USA
Roberto Viau Colindres
Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, MA, USA; Corresponding author.
The CDH1 gene, which encodes E-cadherin, may be associated with cancer when mutated, but the significance of mutations in the context of infection is unknown. In this report, we describe a case of disseminated hypervirulent Klebsiella pneumoniae infection in a 49 year old Caucasian woman with a documented CDH1 mutation.
