Morpho-functional changes in the oxygen-transport system of students at the testing of cardiorespespiration stability

Abstract

The aim of the study was to reveal the character of morpho-functional changes in the oxygen-transport system of students with different levels of cardiorespiratory endurance in conditions of running a 12-minute shuttle run. Material and methods: 80 students (boys 17-19 years) were examined to determine the ventilation function of lungs, gas composition of blood, morphological state of erythrocytes, activity of lipid peroxides, content of 2,3-DPG and ATP in erythrocytes. Results: in students with lower average and low cardiorespiratory endurance after maximum physical exertion, changes in “flow-volume” parameters are observed against a background of increased lactate concentration and a decrease in acid-base balance, which leads to an increase in the content of 2,3-DPG in peripheral blood erythrocytes. Conclusion. It has been established that in students with a lower average and low cardiorespiratory endurance during the 12-minute shuttle run, the growth of lung ventilation is mainly due to an increase in the respiratory rate, which leads to rapid fatigue of the respiratory muscles and, as a consequence, reduced ventilation and gas exchange . At the same time, the level of oxygenation of the blood drops, the intensity of oxidative phosphorylation and the resynthesis of ATP decreases, which leads to the appearance of atypical forms of erythrocytes of peripheral blood.

Keywords

• студенты, гемоглобин, эритроциты, гипоксия, газообмен