Cell Regeneration (Jan 2025)
Standard: Human gastric organoids
- Fan Hong,
- Ronghui Tan,
- Ting Wang,
- Nanshan Zhong,
- Hongling Zhao,
- Rui-hua Xu,
- Lin Shen,
- Yingbin Liu,
- Xuebiao Yao,
- Dongxi Xiang,
- Lijian Hui,
- Jianping Xiong,
- Dong Gao,
- Bing Zhao,
- Zhifeng Miao,
- Jie Hao,
- Yong Li,
- Shijun Hu,
- Boqiang Fu,
- Guoqiang Hua,
- Lei Wang,
- Zhao-Lei Zeng,
- Chong Chen,
- Jianmin Wu,
- Changlin Wang,
- Chunnian Wang,
- Xianbao Zhan,
- Chen Song,
- Chunping Yu,
- Yingying Yang,
- Gengming Niu,
- Yalong Wang,
- Tongbiao Zhao,
- Ye-Guang Chen
Affiliations
- Fan Hong
- Guangzhou National Laboratory
- Ronghui Tan
- Guangzhou National Laboratory
- Ting Wang
- The State Key Laboratory of Membrane Biology, Tsinghua‑Peking Center for Life Sciences, School of Life Sciences, Tsinghua University
- Nanshan Zhong
- The MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University
- Hongling Zhao
- Beijing Institute for Stem Cell and Regenerative Medicine
- Rui-hua Xu
- State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center
- Lin Shen
- State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Gastrointestinal Oncology, Peking University Cancer Hospital and Institute
- Yingbin Liu
- State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Shanghai Jiaotong University School of Medicine
- Xuebiao Yao
- MOE Key Laboratory of Cellular Dynamics, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China
- Dongxi Xiang
- State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Shanghai Jiaotong University School of Medicine
- Lijian Hui
- School of Life Science and Technology, Shanghai Tech University
- Jianping Xiong
- Department of Oncology, The First Affiliated Hospital of Nanchang University
- Dong Gao
- University of Chinese Academy of Sciences
- Bing Zhao
- The MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University
- Zhifeng Miao
- Department of Surgical Oncology and General Surgery, The First Hospital of China Medical University
- Jie Hao
- National Stem Cell Resource Center, Institute of Zoology, Chinese Academy of Sciences
- Yong Li
- Department of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University
- Shijun Hu
- Department of Cardiovascular Surgery of the First Affiliated Hospital & Institute for Cardiovascular Science, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Suzhou Medical College, Soochow University
- Boqiang Fu
- National Institute of Metrology
- Guoqiang Hua
- Department of Radiation Oncology and Cancer Institute, Fudan University Shanghai Cancer Center Fudan University
- Lei Wang
- Beijing Institute for Stem Cell and Regenerative Medicine
- Zhao-Lei Zeng
- State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center
- Chong Chen
- Gastric Cancer Center and Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- Jianmin Wu
- Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Center for Cancer Bioinformatics, Peking University Cancer Hospital and Institute
- Changlin Wang
- China National Institute of Standardization
- Chunnian Wang
- Department of Gastrointestinal Pathology, Ningbo Diagnostic Pathology Center
- Xianbao Zhan
- Department of Oncology, Changhai Hospital, Second Military Medical University
- Chen Song
- Huayi Regeneration Technology Co., Ltd
- Chunping Yu
- Lilly (China) Research and Development Center
- Yingying Yang
- Qilu Pharmaceutical Co., Ltd
- Gengming Niu
- Shang Hai OneTar Biomedicine Co., Ltd
- Yalong Wang
- Guangzhou National Laboratory
- Tongbiao Zhao
- Beijing Institute for Stem Cell and Regenerative Medicine
- Ye-Guang Chen
- Guangzhou National Laboratory
- DOI
- https://doi.org/10.1186/s13619-024-00218-6
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 9
Abstract
Abstract Organoid technology provides a transformative approach to understand human physiology and pathology, offering valuable insights for scientific research and therapeutic development. Human gastric organoids, in particular, have gained significant interest for applications in disease modeling, drug discovery, and studies of tissue regeneration and homeostasis. However, the lack of standardized quality control has limited their extensive clinical applications. The “Human Gastric Organoids” is part of a series of guidelines for human gastric organoids in China, which establishes comprehensive standards on terminology, technical specifications, testing methods, inspection rules, usage instructions, labeling, transportation, and storage, developed by experts from the Chinese Society for Cell Biology and its branch societies. Released on October 29, 2024, this guideline aims to establish standardized protocols, enhance institutional practices, and promote international standardization for clinical and research applications of human gastric organoids.
Keywords