Protocol for a phase 3 trial to evaluate the effectiveness and safety of a heterologous, two-dose vaccine for Ebola virus disease in the Democratic Republic of the Congo

• ,
• Deborah Watson-Jones,
• Shelley Lees,
• Brian Greenwood,
• Daniel G Bausch,
• Peter G Smith,
• Chrissy H Roberts,
• Nathalie Imbault,
• Anton Camacho,
• W John Edmunds,
• Eric Delaporte,
• Melanie Saville,
• John Johnson,
• Ira M Longini,
• Hugo Kavunga-Membo,
• Rebecca F Grais,
• Steve Ahuka,
• Natalie Roberts,
• Edward M Choi,
• Tansy Edwards,
• Maarten Leyssen,
• Bart Spiessens,
• Kerstin Luhn,
• Macaya Douoguih,
• Richard Hatchett,
• Jean-Jacques Muyembe,
• W John Edmunds,
• Daniela Manno,
• Rebecca Grais,
• Susan Rattigan,
• Grace Mambula,
• Patient Mumbere Kighoma,
• Marie Burton,
• Gerald Voss

Affiliations

Deborah Watson-Jones

1 Mwanza Intervention Trials Unit, Mwanza, Tanzania

Shelley Lees

Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK

Brian Greenwood

Department of Disease Control, London School of Hygiene and Tropical Medicine, Faculty of Infectious and Tropical Diseases, London, UK

Daniel G Bausch

UK Public Health Rapid Support Team, London School of Hygiene & Tropical Medicine/Public Health England, London, UK

Peter G Smith

MRC International Statistics and Epidemiology Group, London School of Hygiene & Tropical Medicine, London, UK

Chrissy H Roberts

Clinical Research, London School of Hygiene & Tropical Medicine, London, UK

Nathalie Imbault

CEPI, Oslo, Norway

Anton Camacho

Epicentre, Paris, Île-de-France, France

W John Edmunds

Modelling & Economics Unit, Health Protection Agency, 61 Colindale Avenue, Colindale, London NW9 5EQ, UK

Eric Delaporte

Laboratoire Rétrovirus, Institut de Recherche pour le Développement (IRD) Montpellier, France and University of Montpellier

Melanie Saville

Enteric and Respiratory Virus Laboratory, CPHL, London, UK

John Johnson

Ira M Longini

professor

Hugo Kavunga-Membo

L’Institut National de Recherche Biomédicale, Goma, Democratic Republic of the Congo

Rebecca F Grais

Epicentre, Paris, Île-de-France, France

Steve Ahuka

L’Institut National de Recherche Biomédicale, Goma, Democratic Republic of the Congo

Natalie Roberts

MSF, Paris, France

Edward M Choi

London School of Hygiene & Tropical Medicine, London, UK

Tansy Edwards

London School of Hygiene & Tropical Medicine, London, UK

Maarten Leyssen

Janssen Vaccines and Prevention BV, Leiden, Zuid-Holland, The Netherlands

Bart Spiessens

Janssen Vaccines and Prevention BV, Leiden, Zuid-Holland, The Netherlands

Kerstin Luhn

Janssen Vaccines and Prevention BV, Leiden, Zuid-Holland, The Netherlands

Macaya Douoguih

Janssen Vaccines and Prevention BV, Leiden, Zuid-Holland, The Netherlands

Richard Hatchett

Coalition for Epidemic Preparedness Innovations, Oslo, Norway

Jean-Jacques Muyembe

L’Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo

W John Edmunds

Daniela Manno

Rebecca Grais

Susan Rattigan

Grace Mambula

Patient Mumbere Kighoma

Marie Burton

Gerald Voss