831 E3 ubiquitin ligase Cbl-b deficient CD8+ T cells overcome Treg cell-mediated suppression through IFN-γ and induce robust anti-tumor immunity

• SeongJun Han,
• Zhe Qi Liu,
• Douglas Chung,
• Michael St Paul,
• Carlos Garcia-Batres,
• Azin Sayad,
• Alisha Elford,
• Matthew Gold,
• Natasha Grimshaw,
• Pamela Ohashi

Affiliations

SeongJun Han

1University of Toronto, Toronto, Canada

Zhe Qi Liu

1University of Toronto, Toronto, Canada

Douglas Chung

1University of Toronto, Toronto, Canada

Michael St Paul

2Princess Margaret Cancer Centre, Toronto, Canada

Carlos Garcia-Batres

2Princess Margaret Cancer Centre, Toronto, Canada

Azin Sayad

2Princess Margaret Cancer Centre, Toronto, Canada

Alisha Elford

2Princess Margaret Cancer Centre, Toronto, Canada

Matthew Gold

2Princess Margaret Cancer Centre, Toronto, Canada

Natasha Grimshaw

2Princess Margaret Cancer Centre, Toronto, Canada

Pamela Ohashi

2Princess Margaret Cancer Centre, Toronto, Canada