Nature Communications (Jun 2021)
Hakai is required for stabilization of core components of the m6A mRNA methylation machinery
Abstract
The E3 ligase Hakai can interact with the m6A methylation machinery but its function is still unclear. Here, the authors show that Hakai is a conserved component of the m6A methyltransferase complex and provide functional and molecular insights into its role in regulating m6A levels in Drosophila.