Frontiers in Microbiology (Jul 2022)

A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical China

  • Lun-Sha Deng,
  • Wen-Jie Yu,
  • Nian-Kai Zeng,
  • Yi-Zhe Zhang,
  • Xiao-Peng Wu,
  • Hai-Jiao Li,
  • Fei Xu,
  • Yu-Guang Fan

DOI
https://doi.org/10.3389/fmicb.2022.923435
Journal volume & issue
Vol. 13

Abstract

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Currently, mushroom poisoning still poses a huge problem to humans' health and life globally. Poisoning incidents caused by Inosperma spp. were reported continuously in tropical China in recent years. In this study, a new poisonous Inosperma species, discovered from a poisoning incident, was described in tropical China based on morphological, molecular, and toxin detection evidence; detailed descriptions, photographs, and comparisons to closely related species were provided. For qualitative analysis, through targeted screening using ultra-high liquid chromatography triple quadrupole mass spectrometry (UPLC-MS/MS), the new species contains muscarine and no other toxins (two isoxazole derivatives, two tryptamine alkaloids, three amatoxins, and three phallotoxins). For quantitative analysis, muscarine contents in the pileus and the stipe were 2.08 ± 0.05 and 6.53 ± 1.88 g/kg, respectively.

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