Frontiers in Pharmacology (Aug 2022)

Bioactive natural products in COVID-19 therapy

  • Zhonglei Wang,
  • Zhonglei Wang,
  • Ning Wang,
  • Liyan Yang,
  • Xian-qing Song

DOI
https://doi.org/10.3389/fphar.2022.926507
Journal volume & issue
Vol. 13

Abstract

Read online

The devastating COVID-19 pandemic has caused more than six million deaths worldwide during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic bullets still do not exist. Numerous natural products (cordycepin, gallinamide A, plitidepsin, telocinobufagin, and tylophorine) have been widely studied and play a potential function in treating COVID-19. In this paper, we reviewed published studies (from May 2021 to April 2022) relating closely to bioactive natural products (isolated from medicinal plants, animals products, and marine organisms) in COVID-19 therapy in vitro to provide some essential guidance for anti-SARS-CoV-2 drug research and development.

Keywords