Zaporožskij Medicinskij Žurnal (Apr 2017)

Enteroviral infections: modern clinical, epidemiological features

  • E. V. Usacheva,
  • E. V. Ryabokon,
  • A. M. Kamyshny,
  • D. A. Zadiraka,
  • T. M. Pakholchuk,
  • О. М. Firulina

DOI
https://doi.org/10.14739/2310-1210.2017.2.95681
Journal volume & issue
no. 2
pp. 162 – 167

Abstract

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It has been a clear increase in the number of enteroviral infection (EI) activation in recent years. EI are the widespread agents of infectious diseases in children and adults. Moreover this virus affects various organs and tissues and it results in different symptoms of EI in patients of different age groups. All these facts lead to the difficulties in diagnostics, treatment and prophylactics of the EI clinical forms. Aim of the study was to improve diagnostics of the enteroviral infections (EVI) in children and adults based on the epidemiological features of the definitive clinical forms in season 2016. Materials and Methods. The study was carried out as a part of the Grant Agreement between Zaporizhzhia State Medical University (ZSMU) and "Regional Training Centre of Research in the HealthCare System" (theRepublic ofKazakhstan). 185 patient’s medical documentation was analyzed in the inpatient department. Only symptomatic patients with clinical manifestation of enteroviral infection different forms were included into the study. Polymerase chain reaction (PCR) was used for enteroviruses detection. Results and Discussion: Enterovirus was identified in biological liquids in 36.7 % (68 patients) of cases. Patients with meningitis (35) prevailed among them. Other 9 patients had: exanthema, gastroenteritis, herpangina. An increase in the incidence of morbidity has been noted in August - November with the prevalence of meningitis in August – September, herpangina – in November. Most frequently EVI was detected in children aged 7 – 12 years and in young children. Meningitis dominated in school-aged children, exanthema – in children up to 3 years old. Conclusions. EVI is widespread cause of meningitis, vesicular or ulcerative lesions of the posterior oropharyngeal structures and exanthemas in young and early school-age children. Clear association between season and age features with type of the EVI clinical manifestation has been noted. enteroviral infection; epidemiology; adults; children

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