Nature Communications (Mar 2023)
Evolutionary differentiation of androgen receptor is responsible for sexual characteristic development in a teleost fish
- Yukiko Ogino,
- Satoshi Ansai,
- Eiji Watanabe,
- Masaki Yasugi,
- Yukitoshi Katayama,
- Hirotaka Sakamoto,
- Keigo Okamoto,
- Kataaki Okubo,
- Yasuhiro Yamamoto,
- Ikuyo Hara,
- Touko Yamazaki,
- Ai Kato,
- Yasuhiro Kamei,
- Kiyoshi Naruse,
- Kohei Ohta,
- Hajime Ogino,
- Tatsuya Sakamoto,
- Shinichi Miyagawa,
- Tomomi Sato,
- Gen Yamada,
- Michael E. Baker,
- Taisen Iguchi
Affiliations
- Yukiko Ogino
- Laboratory of Aquatic Molecular Developmental Biology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University
- Satoshi Ansai
- Graduate School of Life Sciences, Tohoku University
- Eiji Watanabe
- Laboratory of Neurophysiology, National Institute for Basic Biology
- Masaki Yasugi
- Center for Optical Research and Education (CORE), Utsunomiya University, Utsunomiya
- Yukitoshi Katayama
- Ushimado Marine Institute, Graduate School of Natural Science and Technology, Okayama University, Ushimado
- Hirotaka Sakamoto
- Ushimado Marine Institute, Graduate School of Natural Science and Technology, Okayama University, Ushimado
- Keigo Okamoto
- Laboratory of Aquatic Molecular Developmental Biology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University
- Kataaki Okubo
- Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo
- Yasuhiro Yamamoto
- Department of Physiology, Division of Life Sciences, Faculty of Medicine, Osaka Medical College
- Ikuyo Hara
- Laboratory of Bioresources, National Institute for Basic Biology
- Touko Yamazaki
- Laboratory of Bioresources, National Institute for Basic Biology
- Ai Kato
- Center of Interuniversity Bio-Backup Project, National Institute for Basic Biology
- Yasuhiro Kamei
- Department of Basic Biology, Graduate University for Advanced Studies (SOKENDAI), Hayama
- Kiyoshi Naruse
- Department of Basic Biology, Graduate University for Advanced Studies (SOKENDAI), Hayama
- Kohei Ohta
- Laboratory of Marine Biology, Faculty of Agriculture, Kyushu University
- Hajime Ogino
- Amphibian Research Center/Graduate School of Integrated Sciences for Life, Hiroshima University
- Tatsuya Sakamoto
- Ushimado Marine Institute, Graduate School of Natural Science and Technology, Okayama University, Ushimado
- Shinichi Miyagawa
- Faculty of Advanced Engineering, Tokyo University of Science
- Tomomi Sato
- Graduate School of Nanobioscience, Yokohama City University
- Gen Yamada
- Department of Developmental Genetics, Institute of Advanced Medicine, Wakayama Medical University
- Michael E. Baker
- Division of Nephrology-Hypertension, School of Medicine, University of California, San Diego
- Taisen Iguchi
- Graduate School of Nanobioscience, Yokohama City University
- DOI
- https://doi.org/10.1038/s41467-023-37026-6
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 16
Abstract
How has the genome duplication impacted the diversification of sexual characteristics in the teleost lineage? This study shows that androgen receptor ohnologs in medaka appear to have diverged in their roles for regulating morphological and behavioural sexual characteristics after loss from an ancestral role in spermatogenesis.
