Dobutamine-Induced Myoclonus in a Patient With Advanced Heart Failure and Chronic Kidney Disease

Alexander Y. Lee, MD; Shiva Barforoshi, MD; Alvin Singh, MD; Ritesh Shrestha, MD; James Ha, MD; Michelle Kittleson, MD, PhD

JACC: Case Reports (Mar 2024)

Dobutamine-Induced Myoclonus in a Patient With Advanced Heart Failure and Chronic Kidney Disease

Alexander Y. Lee, MD,
Shiva Barforoshi, MD,
Alvin Singh, MD,
Ritesh Shrestha, MD,
James Ha, MD,
Michelle Kittleson, MD, PhD

Affiliations

Alexander Y. Lee, MD: Department of Internal Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA
Shiva Barforoshi, MD: Department of Internal Medicine, Harbor-UCLA Medical Center, Torrance, California, USA
Alvin Singh, MD: Department of Neurology, UCLA Ronald Reagan Medical Center, Los Angeles, California, USA
Ritesh Shrestha, MD: Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA
James Ha, MD: Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, USA
Michelle Kittleson, MD, PhD: Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA; Address for correspondence: Dr Michelle Kittleson, Cedars-Sinai Heart Institute, 127 S. San Vincente Boulevard, Pavilion, Suite A6100, Los Angeles, California 90048, USA.

Journal volume & issue: Vol. 29, no. 6
p. 102255

Abstract

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Dobutamine is a positive inotropic agent often used in treatment of cardiogenic shock. Although there are well-documented adverse effects, dobutamine-induced myoclonus is a rarely reported phenomenon. Our case offers a direct and temporally related description of myoclonus, with onset observed within hours of dobutamine initiation and complete resolution within minutes of discontinuation.

Published in JACC: Case Reports

ISSN: 2666-0849 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.journals.elsevier.com/jacc-case-reports

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Abstract

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