Seroprevalencia y factores asociados a la infección por Leptospira spp. en población de Moniquirá, Boyacá

Abstract

Introduction: Leptospirosis is a zoonotic disease, produced by the bacterium Leptospira spp; It affects humans with a non-specific symptomatic picture or a subclinical course, being frequent in tropical areas and humid environments. Objective: To determine the prevalence and factors associated with anti - Leptospira spp antibodies in the asymptomatic people of Moniquirá, Boyacá. Materials and methods: Cross-sectional analytical study, a sample of 193 participants was taken from the municipality, previous informed consent, a data collection instrument was applied, sociodemographic and epidemiological factors were induced, in addition, IgM antibodies for Leptospira spp were determined, information was analyzed by absolute, relative frequencies, and the association was determined with an Odds ratio (OR) evaluating significance with p <0.05. Results: A seropositivity was found for 4.7% anti - Leptospira spp. Antibodies (9/193 IC95% 1.71-7.69), having a higher prevalence in the population of meat sellers. In addition, there is a trend towards a higher prevalence of infection among men (OR 1.43 IC 95% 0.35-7.22) under 45 years of age (OR 2.66 IC 95% 0.64 -13.2) from rural areas (OR 1.33 IC 95% 0.32- 5.73). Conclusion: Asymptomatic people with Leptospira infection were identified, which provides relevant data to the department of Boyacá regarding the endemic of this pathology and the surveillance from public health, which suggests to continue with similar studies in the populations with greater frequency of infection, such as meat sellers.

Keywords

• leptospirosis
• leptospira
• epidemiology
• colombia