Efficacy differences of electroacupuncture with single acupoint or matching acupoints for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial
Bo Chen,
Yang Guo,
Xue Zhao,
Li-li Gao,
Bo Li,
Tian-yi Zhao,
Qi-wen Zhang,
Jin-xing Zou,
Ming-yue Li,
Yong-ming Guo,
Yi Guo,
Xing-fan Pan
Affiliations
Bo Chen
Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine
Yang Guo
The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Xue Zhao
Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine
Li-li Gao
Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine
Bo Li
Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine
Tian-yi Zhao
Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine
Qi-wen Zhang
Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine
Jin-xing Zou
Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine
Ming-yue Li
Clinical Practice Teaching Department of Tianjin University of Traditional Chinese Medicine
Yong-ming Guo
Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine
Yi Guo
Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine
Xing-fan Pan
Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine
Abstract Background Previous studies have shown that acupuncture is beneficial for the alleviation of chemotherapy-induced nausea and vomiting. However, there is a lack of clinical evidence concerning the effects of acupoint-matching on chemotherapy-induced nausea and vomiting. Methods/design This is a parallel randomized controlled trial to evaluate the occurrence of nausea and vomiting after chemotherapy (the incidence of nausea and vomiting, frequency, VAS score, RINVR rating) as the main outcome for cancer. Quality of life, anxiety and depression scores are the secondary outcomes. Quality of life, anxiety and depression scores are the secondary phase. Use of remedy drugs, routine blood examination, and blood biochemical tests are the safety evaluation. We also compare the different effects of ST36 (single acupoint), CV12 (single acupoint), and ST36-CV12 matching groups. Discussion The results of this trial are expected to explore the effects of matching different acupoints and to offer biologic plausibility for the use of acupuncture in the treatment of chemotherapy-induced nausea and vomiting (CINV). Trial registration This trial is registered with clinicaltrials.gov NCT02195921 , The date of registration was 17 July 2014.
