Inhibition of the RNA-Dependent RNA-Polymerase from SARS-CoV‑2 by 6‑Chloropurine Isoxazoline-Carbocyclic Monophosphate Nucleotides

• Marco Leusciatti,
• Beatrice Macchi,
• Francesca Marino-Merlo,
• Antonio Mastino,
• Giulia Morra,
• Paolo Quadrelli

Affiliations

Marco Leusciatti

Department of Chemistry, University of Pavia, Pavia, Italy

Beatrice Macchi

Department of Chemical Science and Technology, University of Rome Tor Vergata, Roma, Italy

Francesca Marino-Merlo

Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy

Antonio Mastino

The Institute of Translational Pharmacology, Roma, Italy

Giulia Morra

Biocomputing Lab, SCITEC-Istituto di Scienze e Tecnologie Chimiche CNR, Milano, Italy

Paolo Quadrelli

Department of Chemistry, University of Pavia, Pavia, Italy