Uro (Dec 2022)

Relationship between Androgen Deprivation Therapy and Abdominal Adipose Tissue

  • Federico Greco,
  • Alessandro Tafuri,
  • Andrea Panunzio,
  • Bruno Beomonte Zobel,
  • Carlo Augusto Mallio

DOI
https://doi.org/10.3390/uro2040030
Journal volume & issue
Vol. 2, no. 4
pp. 270 – 276

Abstract

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The role of androgens in body composition is well known. Androgen deprivation therapy (ADT) has shown beneficial effects in the treatment of advanced prostate cancer (PCa). Given that androgens are important for the homeostasis of different organs, the effects of ADT can affect body composition and therefore adipose tissue. Computed tomography (CT) and magnetic resonance imaging (MRI) are non-invasive methods that allow for quantification of the different fat compartments. In this review we describe the effects of ADT on abdominal adipose tissue in PCa patients.

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