Comparison of IQ scores between children with phenylketonuria and healthy children referring to Besat Hospital in Sanandaj between 2017 and 2018

Abstract

Background and Aim:Phenylketonuria is a type of autosomal recessive congenital and genetically induced fungal disease that has not been converted to tyrosine by the lack or lack of the phenylalanine hydroxylase enzyme and has been shown to increase phenylalanine levels in the blood, especially in the brain. The aim of this study was to compare the IQ scores of children with phenylketonuria and healthy children referring to Besat hospital clinic in Sanandaj in 2017-2018.Methods:This historic cohort study wasperformed on all of the patients at the time of birth, referred to PKU and pediatric clinics, as well as healthy children (for phenylketonuria) referred to other clinics of the children's hospital. The control group was done.Goodinow’s intelligence test was used to measure cognitive, mental and children's intelligence. Finally, the results of the two groups were analyzed by the statistical consult.Results:The results showed that 46 (69.7%) were male and 20 (30.3%) were female. The mean age of the subjects was 6.34±2.52of years. Result from the current study showed that there was not significant differences between IQ mean in two groups of study(p>0.05).Conclusion:According to the results of this study, the timely identification and treatment of patients with phenylketonuria has been able to prevent the complications of this disease to a large extent, and keep the children's IQs intact, thereby providing timely andaccurate identification and treatment of this disease is necessary among children.

Keywords

• pku
• iq
• children