Research and Reports in Urology (Jan 2021)
Atypical Locations of Renal Cell Carcinoma Metastases to the Pancreas and Duodenum
Abstract
Łukasz Piskorz,1 Kryspin Mitura,2,3 Witold Olejniczak,1 Piotr Misiak,4 Slawomir Jablonski4 1Department of General Surgery, Brothers of St John of God Hospital, Lodz, Poland; 2Department of General Surgery, Siedlce Hospital, Siedlce, Poland; 3Faculty of Medical and Health Sciences, University of Natural Sciences and Humanities in Siedlce, Siedlce, Poland; 4Clinic of the Chest Surgery, General and Oncological Surgery, Military Medical Academy University Teaching Hospital – Central Veterans’ Hospital, Lodz, PolandCorrespondence: Kryspin Mitura Narutowicza 25, Siedlce 08-110 Tel +48602809035Email [email protected]: Pancreatic tumors account for a small percentage of all malignancies. Most of them are primary and originate from cells of the exocrine pancreas. The remaining primary changes are neuroendocrine tumors. The pancreas may also be a target of metastatic lesions. The most common cancer that metastasizes to the pancreas is renal cell carcinoma.Case Studies: The paper presents two cases of rare metastases to organs of the abdominal cavity: the first patient treated surgically due to two metastatic lesions of renal cell carcinoma in the pancreas, diagnosed many years after radical nephrectomy. The second case of high gastrointestinal obstruction in the course of metastasis of renal cell carcinoma to the duodenum. The first patient underwent distal laparotomic resection of the pancreas. The second patient underwent resection of the duodenum and the first jejunal loop with side-to-side duodeno-jejunal anastomosis. Both patients remain under oncological supervision.Conclusion: Patients after radical nephrectomy due to renal cell carcinoma require long-term systematic monitoring. Due to the anatomical position of the pancreas and duodenum as well as the number, location and size of metastatic lesions, the course of the disease may be initially asymptomatic or oligosymptomatic. Aggressive surgical treatment of pancreatic metastases creates opportunities for long-term survival.Keywords: renal cell carcinoma, metastases, pancreas, duodenum, surgery
