Synthesis and antitubercular activity of some new Quinixaline derivatives

Abstract

A new series of N'-(3-hydroxy-3,4-dihydroquinoxaline-2-carbonyl)-N-phenylcarbamimidic acid derivatives were designed and synthesized. The newly synthesized compounds were evaluated for their anti-tubercular activity. The structure of the synthesized compounds was confirmed by elemental analysis and spectral data (IR, 1H NMR and Mass). The data obtained from biological screening revealed that synthesized compounds showed the good to moderate anti-tubercular activities.

Keywords

• quinixaline derivatives
• anti-tubercular activity