Respiratory Medicine Case Reports (Jan 2017)

Pleural amyloidosis imitating pleural malignancy

  • Frith Coolbear, MBChB,
  • Ana-Maria Bilawich, MD,
  • Jonathan Tongson, MD,
  • James Adamo, MD,
  • Andrew Churg, MD

DOI
https://doi.org/10.1016/j.rmcr.2017.03.004
Journal volume & issue
Vol. 20, no. C
pp. 195 – 197

Abstract

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CT chest performed to investigate dyspnea and malaise in an 83 year old man demonstrated bilateral circumferential pleural thickening highly suspicious for pleural mesothelioma or metastatic pleural malignancy. Histopathology of a subsequent pleural biopsy returned a diagnosis of pleural amyloid. This case identifies pleural amyloid as a rare differential consideration for diffuse pleural thickening; the difficulties in distinguishing pleural amyloid from pleural malignancy are highlighted.

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