Diagnostics (Aug 2021)

Value of Left Atrial Appendage Function Measured by Transesophageal Echocardiography for Prediction of Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation

  • Sabina Istratoaie,
  • Ștefan C. Vesa,
  • Gabriel Cismaru,
  • Dana Pop,
  • Radu Roșu,
  • Mihai Puiu,
  • Diana Pepine,
  • Cristina Ciobanu,
  • Ioan A. Minciuna,
  • Gelu Simu,
  • Dumitru Zdrenghea,
  • Anca D. Buzoianu

DOI
https://doi.org/10.3390/diagnostics11081465
Journal volume & issue
Vol. 11, no. 8
p. 1465

Abstract

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Atrial fibrillation (AF) recurrence after radiofrequency catheter ablation (RFCA) remains a challenging issue. This study aims to explore the left atrial appendage function by transesophageal echocardiography (TEE) and assess its value in predicting AF recurrence following RFCA in paroxysmal AF patients. Eighty-one patients with paroxysmal AF that underwent RFCA were recruited. TEE was performed before ablation with the assessment of left atrial appendage emptying flow velocity (LAAeV). AF recurrence occurred in 24 patients (29.6%) within 12 months after RFCA. The left atrium diameter (LAD) and left atrium volume index (LAVI) were both significantly higher in the recurrence group compared to the non-recurrence group, while the LAAeV was significantly lower in the recurrence group. LAD, LAVi and LAAeV were univariately significant risk factors for AF recurrence after ablation. Based on receiver operating curve (ROC), LAAeV 40.5 mL and LAD > 41 mm were identified as cut-off values for predicting AF recurrence. In multivariate regression analysis LAAeV p 40.5 mL and LAD > 41 mm (p = 0.319; p = 0.507, respectively). A low LAAeV was the only important independent predictor of AF recurrence within 1 year after first RFCA.

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