Tuning Co/Ni Ratio in Co–Ni Bimetallic Hybrid for Electrochemical Detection of Glucose
Junyi Zeng,
Yanting Yang,
Xiaoyu Lei,
Jinan Deng,
Ning Hu,
Jun Yang
Affiliations
Junyi Zeng
Key Laboratory of Biorheological Science and Technology, Ministry of Education and Bioengineering College, Chongqing University, Chongqing 400030, China
Yanting Yang
College of Animal Science and Technology, Southwest University, Chongqing 402460, China
Xiaoyu Lei
Key Laboratory of Biorheological Science and Technology, Ministry of Education and Bioengineering College, Chongqing University, Chongqing 400030, China
Jinan Deng
Key Laboratory of Biorheological Science and Technology, Ministry of Education and Bioengineering College, Chongqing University, Chongqing 400030, China
Ning Hu
Key Laboratory of Biorheological Science and Technology, Ministry of Education and Bioengineering College, Chongqing University, Chongqing 400030, China
Jun Yang
Key Laboratory of Biorheological Science and Technology, Ministry of Education and Bioengineering College, Chongqing University, Chongqing 400030, China
Transition metallic binary alloys have attracted enormous attention in regard to the non-enzymatic detection of glucose due to their high electrocatalytic activities induced by the synergistic effect between the individual metallic species. However, the easy aggregation of the bimetallic particles has limited their performance. Herein, a facile metal–organic framework (MOF)-derived strategy is developed to synthesize a hybrid containing binary Co–Ni nanoparticles decorated on an N-doped porous carbon matrix (CoxNiy/N-C) for the non-enzymatic detection of glucose. The Co/Ni ratio in the hybrid is investigated to regulate its electrocatalytic behaviors for glucose sensing. A hybrid with the optimal Co/Ni ratio of 1:1 displays two linear detection ranges (0.5 µM to 1 mM and 1 mM to 10 mM) with a detection limit of 0.11 µM for glucose. The feasibility of using this hybrid-modified SPE for glucose detection in real serum samples has also been validated.
