Myeloma natural killer cells are exhausted and have impaired regulation of activation

• Criselle D’Souza,
• Simon P. Keam,
• Han Xian Aw Yeang,
• Michael Neeson,
• Kelden Richardson,
• Andy K. Hsu,
• Rachael Canfield,
• Natalie Bezman,
• Michael Robbins,
• Hang Quach,
• David S. Ritchie,
• Simon J. Harrison,
• Joseph A. Trapani,
• H. Miles Prince,
• Paul A. Beavis,
• Phillip K. Darcy,
• Paul J. Neeson

Affiliations

Criselle D’Souza

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne

Simon P. Keam

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Australia; Tumour Suppression and Cancer Sex Disparity Laboratory, Peter MacCallum Cancer Centre, Melbourne

Han Xian Aw Yeang

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne

Michael Neeson

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne

Kelden Richardson

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne

Andy K. Hsu

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne

Rachael Canfield

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne

Natalie Bezman

Oncology Discovery Research, Bristol-Myers Squibb, Redwood City, CA, USA. Current: Arsenal Bio, San Francisco, CA 94080

Michael Robbins

Translational Medicine, Bristol-Myers Squibb, Cambridge, MA, USA, (current: io904 LLC)

Hang Quach

Department of Hematology, St Vincent’s Hospital, Melbourne, Australia; Faculty of Medicine, University of Melbourne

David S. Ritchie

Tumour Suppression and Cancer Sex Disparity Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia; Faculty of Medicine, University of Melbourne, Australia; Clinical Hematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne

Simon J. Harrison

Tumour Suppression and Cancer Sex Disparity Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia; Clinical Hematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne

Joseph A. Trapani

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne

H. Miles Prince

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Australia; Clinical Hematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne

Paul A. Beavis

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne

Phillip K. Darcy

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne

Paul J. Neeson

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne