Advances of Hydrogel Therapy in Periodontal Regeneration—A Materials Perspective Review
Maoxue Li,
Jiaxi Lv,
Yi Yang,
Guoping Cheng,
Shujuan Guo,
Chengcheng Liu,
Yi Ding
Affiliations
Maoxue Li
State Key Laboratory of Oral Diseases, Department of Periodontics, West China School & Hospital of Stomatology, Sichuan University, Chengdu 610041, China
Jiaxi Lv
State Key Laboratory of Oral Diseases, Department of Periodontics, West China School & Hospital of Stomatology, Sichuan University, Chengdu 610041, China
Yi Yang
State Key Laboratory of Oral Diseases, Department of Periodontics, West China School & Hospital of Stomatology, Sichuan University, Chengdu 610041, China
Guoping Cheng
State Key Laboratory of Oral Diseases, Department of Periodontics, West China School & Hospital of Stomatology, Sichuan University, Chengdu 610041, China
Shujuan Guo
State Key Laboratory of Oral Diseases, Department of Periodontics, West China School & Hospital of Stomatology, Sichuan University, Chengdu 610041, China
Chengcheng Liu
State Key Laboratory of Oral Diseases, Department of Periodontics, West China School & Hospital of Stomatology, Sichuan University, Chengdu 610041, China
Yi Ding
State Key Laboratory of Oral Diseases, Department of Periodontics, West China School & Hospital of Stomatology, Sichuan University, Chengdu 610041, China
Hydrogel, a functional polymer material, has emerged as a promising technology for therapies for periodontal diseases. It has the potential to mimic the extracellular matrix and provide suitable attachment sites and growth environments for periodontal cells, with high biocompatibility, water retention, and slow release. In this paper, we have summarized the main components of hydrogel in periodontal tissue regeneration and have discussed the primary construction strategies of hydrogels as a reference for future work. Hydrogels provide an ideal microenvironment for cells and play a significant role in periodontal tissue engineering. The development of intelligent and multifunctional hydrogels for periodontal tissue regeneration is essential for future research.
