Nature Communications (Sep 2017)

Tbx3-dependent amplifying stem cell progeny drives interfollicular epidermal expansion during pregnancy and regeneration

  • Ryo Ichijo,
  • Hiroki Kobayashi,
  • Saori Yoneda,
  • Yui Iizuka,
  • Hirokazu Kubo,
  • Shigeru Matsumura,
  • Satsuki Kitano,
  • Hitoshi Miyachi,
  • Tetsuya Honda,
  • Fumiko Toyoshima

DOI
https://doi.org/10.1038/s41467-017-00433-7
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 13

Abstract

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The abdominal skin expands rapidly during pregnancy. Here the authors show that a population of highly proliferative stem cell progenies expressing the transcription factor Tbx3 is required for abdominal skin expansion in pregnant mice.