Gastrointestinal Stromal Tumor in Pregnancy: A Rare Case with Review of Literature

Abstract

Gastrointestinal stromal tumors (GISTs) are rare and these tumors are mesenchymal tumors that develop in the wall of the GI tract. The aim of this study was to report a case with GIST in pregnancy in Western Iran. A 39-year-old pregnant female (G5 P4) was admitted with a chief complaint of abdominal pain and epigastric fullness on 12th April 2016. Sonography showed gestational age of 15w+1d and solid cystic intra abdominal mass is extending from epigastrium in the midline to left upper quadrant. Abdominal MRI on 20th April, showed a solid mass measuring 24x15x12.5cm with smooth and well-defined border. Pathology report on 29th May 2016, showed a gross large mass measuring 24x19x10cm attached to a segment of stomach measuring 20x8cm with heterogenous cystic hemorrhagic cut surface of the tumor. Microscopic pathology reported: compatible with gastrointestinal stromal tumor, group 3b (Intermediate risk) according to Miettinen risk classification. In conclusion, pregnant GIST is very rare and therefore, diagnostic information about risk factors for them is very low, but CD117+/ CD34+ can be an important diagnostic sign for pregnant GIST.

Keywords

• Gastrointestinal stromal tumor
• Pregnancy
• Case report