Immune Response in Severe Infection: Could Life-Saving Drugs Be Potentially Harmful?

Maja Surbatovic; Jasna Jevdjic; Milic Veljovic; Nada Popovic; Dragan Djordjevic; Sonja Radakovic

doi:10.1155/2013/961852

The Scientific World Journal (Jan 2013)

Immune Response in Severe Infection: Could Life-Saving Drugs Be Potentially Harmful?

Maja Surbatovic,
Jasna Jevdjic,
Milic Veljovic,
Nada Popovic,
Dragan Djordjevic,
Sonja Radakovic

Affiliations

Maja Surbatovic: Clinic of Anesthesiology and Intensive Therapy, Military Medical Academy, Crnotravska 17, 11000 Belgrade, Serbia
Jasna Jevdjic: Clinical Center Kragujevac, Zmaj Jovina 30, 34000 Kragujevac, Serbia
Milic Veljovic: Clinic of Anesthesiology and Intensive Therapy, Military Medical Academy, Crnotravska 17, 11000 Belgrade, Serbia
Nada Popovic: Institute for Infectious and Tropical Diseases, Intensive Care Unit, Clinical Center of Serbia, Pasterova 2, 11000 Belgrade, Serbia
Dragan Djordjevic: Clinic of Anesthesiology and Intensive Therapy, Military Medical Academy, Crnotravska 17, 11000 Belgrade, Serbia
Sonja Radakovic: Faculty of Medicine of the Military Medical Academy, University of Defense, Crnotravska 17, 11000 Belgrade, Serbia

DOI: https://doi.org/10.1155/2013/961852
Journal volume & issue: Vol. 2013

Abstract

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Critically ill patients suffer a high rate of nosocomial infection with secondary sepsis being a common cause of death. Usage of antibiotics and catecholamines is often necessary, but it can compromise complex immune response to infection. This review explores influence of these life-saving drugs on host immune response to severe infection.

Published in The Scientific World Journal

ISSN: 2356-6140 (Print); 1537-744X (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Technology; Medicine; Science
Website: https://onlinelibrary.wiley.com/journal/8086

About the journal