Reseach in the Sphere of Perspective Use of Biochemical and Medical Biocatalytic Technologies in the Interests of Armed Forces

Abstract

The article is dedicated to the review of the theoretical and experimental research of the Russian and foreign scientists in the enzymes both in native state and in forms of chemically stabilized nanosized particles, promising for the development of military products of different types. It summarises the results of use of biocatalysts on the basis of enzymes and microorganisms­destructors for the neutralization of eco­toxicants. The nature of enzymes is analyzed. The significant part of the article is dedicated to the data obtained regarding the sphere of biochemical and medical biocatalytic technologies for the development of enzymatic prophylactic and therapeutic means. A special attention is paid to the enzymes, used in protective equipment, to environmental biocatalysts, to biopharmaceuticals on the basis of enzymes and microorganisms­destructors for the utilization of reaction masses, to chemical detoxification of poisonous substances. The authors point out the main trends in the further research in the sphere of biotechnologies: enzymatic pharmaceuticals for prophylaxis and treatment of OP poisoning; enzymes in self­degassing materials and in protective equipment; biocatalysts for soil, water and surface purification; biopharmaceuticals on the basis of enzymes and microorganisms­destructors for the degradation of reaction masses of toxic chemicals.

Keywords

• bacteria pseudomonas sp. 78g
• environmental biocatalysts
• hexahistidine-tagged organophosphate hydrolase (his6-oph)
• microorganisms-destructors of toxic chemicals
• selfdegassing materials
• biocatalysts of chemical reactions in organism
• enzymatic antidotes of op substances
• enzymatic components of protective equipment
• enzymatic catalysts of the destruction of the reaction masses of op substances
• organophosphorus (op) toxic chemicals