Nature Communications (May 2022)

Extended intergenic DNA contributes to neuron-specific expression of neighboring genes in the mammalian nervous system

  • Ravneet Jaura,
  • Ssu-Yu Yeh,
  • Kaitlin N. Montanera,
  • Alyssa Ialongo,
  • Zobia Anwar,
  • Yiming Lu,
  • Kavindu Puwakdandawa,
  • Ho Sung Rhee

DOI
https://doi.org/10.1038/s41467-022-30192-z
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 18

Abstract

Read online

A large part of noncoding DNA is intergenic regions, yet how the size of intergenic regions affects gene expression in a tissue-specific manner is unclear. Here the authors present long intergenic DNA length-dependent neural gene expression, reflecting the complexity in the mammalian nervous system.