Química Nova (Jan 2008)

Natural occurrence, biological activities and synthesis of eight-, nine-, and eleven-membered ring lactones

  • Helena M. C. Ferraz,
  • Fernanda I. Bombonato,
  • Myrian K. Sano,
  • Luiz S. Longo Jr.

DOI
https://doi.org/10.1590/S0100-40422008000400029
Journal volume & issue
Vol. 31, no. 4
pp. 885 – 900

Abstract

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The natural occurrence, biological activities and synthetic approaches to natural eight-, nine-, and eleven-membered lactones is reviewed. These medium ring lactones are grouped according to ring size, and their syntheses are discussed. The structures of some natural products early identified as medium-ring lactones were revised after total synthesis.

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