Communications Biology (Aug 2022)
Modeling SARS-CoV-2 and influenza infections and antiviral treatments in human lung epithelial tissue equivalents
- Hoda Zarkoob,
- Anna Allué-Guardia,
- Yu-Chi Chen,
- Andreu Garcia-Vilanova,
- Olive Jung,
- Steven Coon,
- Min Jae Song,
- Jun-Gyu Park,
- Fatai Oladunni,
- Jesse Miller,
- Yen-Ting Tung,
- Ivan Kosik,
- David Schultz,
- James Iben,
- Tianwei Li,
- Jiaqi Fu,
- Forbes D. Porter,
- Jonathan Yewdell,
- Luis Martinez-Sobrido,
- Sara Cherry,
- Jordi B. Torrelles,
- Marc Ferrer,
- Emily M. Lee
Affiliations
- Hoda Zarkoob
- 3D Tissue Bioprinting Lab, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health
- Anna Allué-Guardia
- Host-Pathogen Interactions and Population Health Programs, Texas Biomedical Research Institute
- Yu-Chi Chen
- 3D Tissue Bioprinting Lab, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health
- Andreu Garcia-Vilanova
- Host-Pathogen Interactions and Population Health Programs, Texas Biomedical Research Institute
- Olive Jung
- 3D Tissue Bioprinting Lab, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health
- Steven Coon
- Molecular Genomics Core, National Institute of Child Health and Human Development, National Institutes of Health
- Min Jae Song
- 3D Tissue Bioprinting Lab, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health
- Jun-Gyu Park
- Host-Pathogen Interactions and Population Health Programs, Texas Biomedical Research Institute
- Fatai Oladunni
- Host-Pathogen Interactions and Population Health Programs, Texas Biomedical Research Institute
- Jesse Miller
- Department of Biochemistry and Biophysics, University of Pennsylvania
- Yen-Ting Tung
- 3D Tissue Bioprinting Lab, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health
- Ivan Kosik
- National Institute for Allergies and Infectious Diseases, National Institutes of Health
- David Schultz
- Department of Biochemistry and Biophysics, University of Pennsylvania
- James Iben
- Molecular Genomics Core, National Institute of Child Health and Human Development, National Institutes of Health
- Tianwei Li
- Molecular Genomics Core, National Institute of Child Health and Human Development, National Institutes of Health
- Jiaqi Fu
- 3D Tissue Bioprinting Lab, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health
- Forbes D. Porter
- Section on Molecular Dysmorphology, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services
- Jonathan Yewdell
- National Institute for Allergies and Infectious Diseases, National Institutes of Health
- Luis Martinez-Sobrido
- Host-Pathogen Interactions and Population Health Programs, Texas Biomedical Research Institute
- Sara Cherry
- Department of Biochemistry and Biophysics, University of Pennsylvania
- Jordi B. Torrelles
- Host-Pathogen Interactions and Population Health Programs, Texas Biomedical Research Institute
- Marc Ferrer
- 3D Tissue Bioprinting Lab, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health
- Emily M. Lee
- 3D Tissue Bioprinting Lab, Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health
- DOI
- https://doi.org/10.1038/s42003-022-03753-7
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 17
Abstract
Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms.
