Histopathological Evaluation of the Effect of Eugenol in a Model of Trinitrobenzenesulfonic Acid-Induced Colitis in Rats

Marinov V.; Tzaneva M.; Zhelyazkova-Savova M.; Gancheva S.; Valcheva-Kuzmanova St.

doi:10.2478/amb-2021-0042

Acta Medica Bulgarica (Nov 2021)

Histopathological Evaluation of the Effect of Eugenol in a Model of Trinitrobenzenesulfonic Acid-Induced Colitis in Rats

Marinov V.,
Tzaneva M.,
Zhelyazkova-Savova M.,
Gancheva S.,
Valcheva-Kuzmanova St.

Affiliations

Marinov V.: Department of Pharmacology and Clinical Pharmacology and Therapeutics, Faculty of Medicine, Medical University Prof. Dr. Paraskev Stoyanov – Varna, Bulgaria
Tzaneva M.: Department of General and Clinical Pathology, Forensic Medicine and Deontology, Faculty of Medicine, Medical University Prof. Dr. Paraskev Stoyanov – Varna, Bulgaria
Zhelyazkova-Savova M.: Department of Pharmacology and Clinical Pharmacology and Therapeutics, Faculty of Medicine, Medical University Prof. Dr. Paraskev Stoyanov – Varna, Bulgaria
Gancheva S.: Department of Pharmacology and Clinical Pharmacology and Therapeutics, Faculty of Medicine, Medical University Prof. Dr. Paraskev Stoyanov – Varna, Bulgaria
Valcheva-Kuzmanova St.: Department of Pharmacology and Clinical Pharmacology and Therapeutics, Faculty of Medicine, Medical University Prof. Dr. Paraskev Stoyanov – Varna, Bulgaria

DOI: https://doi.org/10.2478/amb-2021-0042
Journal volume & issue: Vol. 48, no. 4
pp. 9 – 14

Abstract

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Introduction: Trinitrobenzenesulfonic acid (TNBS)-induced experimental colitis in animals is a commonly used model of inflammatory bowel disease (IBD). Eugenol (Eug) is a natural phenolic compound possessing promising antioxidant and anti-inflammatory therapeutic properties.

Published in Acta Medica Bulgarica

ISSN: 0324-1750 (Print); 2719-5384 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Medicine
Website: https://sciendo.com/journal/AMB

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Abstract

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