Indian Journal of Ophthalmology (Jan 2013)

Distant metastatic retinoblastoma without central nervous system involvement

  • Mohammad Javed Ali,
  • Santosh G Honavar,
  • Vijay Anand Reddy

DOI
https://doi.org/10.4103/0301-4738.97077
Journal volume & issue
Vol. 61, no. 7
pp. 357 – 359

Abstract

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Retinoblastoma is the most common intraocular malignancy in children, with a reported incidence ranging from 1 in 15,000 to 1 in 18,000 live births. Metastatic retinoblastoma is rare in developed countries, with a reported range from 4.8% in the United States to 5.8% in the United Kingdom. However, the frequency reported from developing countries varies from 9 to 11% at presentation. The mortality is very high owing to late presentations, delayed diagnosis compounded by socio-economic factors. The management of metastatic retinoblastoma is evolving, but it is still a challenge in pediatric oncology. We present a case of an extensive skeletal metastasis that initially presented as a massive orbital retinoblastoma.

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