Case Reports in Dentistry (Jan 2022)

Repeated Occurrence and Recurrence of Secondary Oral Solid Cancers after Hematopoietic Stem Cell Transplantation for Leukaemia: Long-Term Follow-Up

  • Takumi Takahashi,
  • Miki Yamada,
  • Keisuke Sawada,
  • Nami Nakayama,
  • Yosuke Iijima,
  • Shunsuke Hino,
  • Takahiro Kaneko,
  • Norio Horie

DOI
https://doi.org/10.1155/2022/9592077
Journal volume & issue
Vol. 2022

Abstract

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Hematopoietic stem cell transplantation (HSCT) is a common method for patients such as hematologic malignancies. However, HSCT generally has a higher risk of secondary solid cancer development. The aim of this study was to emphasize the need for lifelong follow-up of oral secondary solid cancer. The patient was a male who underwent HSCT for chronic myelogenous leukaemia at the age of 31 years. He underwent ten onsets on oral secondary solid cancers during his subsequent follow-up of more than 20 years. In conclusion, patients after HSCT require lifelong observation of oral secondary solid cancer, which may be accompanied by repeated new and recurrent occurrences.