WTAP–VIRMA counteracts dsDNA binding of the m6A writer METTL3–METTL14 complex and maintains N 6-adenosine methylation activity

• Xuhui Yan,
• Feiqing Liu,
• Junjun Yan,
• Mengjun Hou,
• Min Sun,
• Delin Zhang,
• Zhou Gong,
• Xu Dong,
• Chun Tang,
• Ping Yin

Affiliations

Xuhui Yan

National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University

Feiqing Liu

National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University

Junjun Yan

National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University

Mengjun Hou

National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University

Min Sun

Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences

Delin Zhang

National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University

Zhou Gong

Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences

Xu Dong

Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences

Chun Tang

College of Chemistry and Molecular Engineering, and Peking-Tsinghua Center for Life Sciences, Peking University

Ping Yin

National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University