644 Tumor-mediated suppressive signaling and hypoxia supports altered chromatin landscapes that limit the transcriptional and functional potential of terminal T cell exhaustion

• Nicole Scharping,
• Greg Delgoffe,
• Paolo Vignali,
• Natalie Rittenhouse,
• Amanda Poholek,
• Rhodes Ford

Affiliations

Nicole Scharping

Aff236 grid.21925.3d0000000419369000University of Pittsburgh Pittsburgh PA USA

Greg Delgoffe

1University of Pittsburgh, Pittsburgh, PA, USA

Paolo Vignali

University of Pittsburgh SOM, Pittsburgh, Pennsylvania, USA

Natalie Rittenhouse

1University Of Pittsburgh, Pittsburgh, PA, USA

Amanda Poholek

1University Of Pittsburgh, Pittsburgh, PA, USA

Rhodes Ford

University of Pittsburgh, Pittsburgh, PA, USA