Nature Communications (Sep 2019)

The marginal cells of the Caenorhabditis elegans pharynx scavenge cholesterol and other hydrophobic small molecules

  • Muntasir Kamal,
  • Houtan Moshiri,
  • Lilia Magomedova,
  • Duhyun Han,
  • Ken C. Q. Nguyen,
  • May Yeo,
  • Jessica Knox,
  • Rachel Bagg,
  • Amy M. Won,
  • Karolina Szlapa,
  • Christopher M. Yip,
  • Carolyn L. Cummins,
  • David H. Hall,
  • Peter J. Roy

DOI
https://doi.org/10.1038/s41467-019-11908-0
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 16

Abstract

Read online

The C. elegans nematode worm is a filter-feeder and requires dietary sources of cholesterol. Here, the authors show that the C. elegans pharynx works as a filter to scavenge hydrophobic small molecules from its surrounding liquid environment.