Antidromic-rectifying gap junctions amplify chemical transmission at functionally mixed electrical-chemical synapses

Ping Liu; Bojun Chen; Roger Mailler; Zhao-Wen Wang

doi:10.1038/ncomms14818

Nature Communications (Mar 2017)

Antidromic-rectifying gap junctions amplify chemical transmission at functionally mixed electrical-chemical synapses

Ping Liu,
Bojun Chen,
Roger Mailler,
Zhao-Wen Wang

Affiliations

Ping Liu: Department of Neuroscience, University of Connecticut Health Center
Bojun Chen: Department of Neuroscience, University of Connecticut Health Center
Roger Mailler: Department of Computer Science, University of Tulsa
Zhao-Wen Wang: Department of Neuroscience, University of Connecticut Health Center

DOI: https://doi.org/10.1038/ncomms14818
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 16

Abstract

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Emerging evidence suggests that chemical and electrical synapses interact to regulate the strength of synaptic transmission. Liuet al. report that in a C. elegansescape circuit, functionally mixed electrical-chemical synapses exist between premotor interneurons and downstream motor neurons, and that the electrical synapse amplifies the chemical transmission between the neurons.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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