Бюллетень сибирской медицины (Feb 2014)

THE ROLE OF MICROBIAL COMMUNITIES OF AIRWAYS IN PATHOGENESIS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

  • S. V. Fedosenko,
  • L. M. Ogorodova,
  • M. A. Karnaushkina,
  • Ye. S. Kulikov,
  • I. A. Deyev,
  • N. A. Kirillova

DOI
https://doi.org/10.20538/1682-0363-2014-1-153-160
Journal volume & issue
Vol. 13, no. 1
pp. 153 – 160

Abstract

Read online

This review summarizes the results of studies on the composition of microbial communities in the airways of healthy subjects and in patients with chronic obstructive pulmonary disease. Modern technologies of molecular-genetic identification methods of microorganisms allow to perform a deep analysis of the respiratory microbiom. It is of considerable interest to determine the role of the microbiome in the development of human diseases of the bronchopulmonary system, and to understand the impact of the microbes communities as a course of disease and the important factor for the efficacy of current therapy.

Keywords