Myeloid malignancies with 5q and 7q deletions are associated with extreme genomic complexity, biallelic TP53 variants, and very poor prognosis

• Beth A. Pitel,
• Neeraj Sharma,
• Cinthya Zepeda-Mendoza,
• James B. Smadbeck,
• Kathryn E. Pearce,
• Joselle M. Cook,
• George Vasmatzis,
• Zohar Sachs,
• Rashmi Kanagal-Shamanna,
• David Viswanatha,
• Sheng Xiao,
• Robert B. Jenkins,
• Xinjie Xu,
• Nicole L. Hoppman,
• Rhett P. Ketterling,
• Jess F. Peterson,
• Patricia T. Greipp,
• Linda B. Baughn

Affiliations

Beth A. Pitel

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic

Neeraj Sharma

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic

Cinthya Zepeda-Mendoza

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic

James B. Smadbeck

Center for Individualized Medicine-Biomarker Discovery, Mayo Clinic

Kathryn E. Pearce

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic

Joselle M. Cook

Department of Medicine, Division of Hematology, Mayo Clinic

George Vasmatzis

Center for Individualized Medicine-Biomarker Discovery, Mayo Clinic

Zohar Sachs

Division of Hematology, Oncology, and Transplantation, Department of Medicine and Masonic Cancer Center, University of Minnesota

Rashmi Kanagal-Shamanna

Department of Hematopathology, University of Texas MD Anderson Cancer Center

David Viswanatha

Department of Laboratory Medicine and Pathology, Division of Hematopathology, Mayo Clinic

Sheng Xiao

Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School

Robert B. Jenkins

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic

Xinjie Xu

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic

Nicole L. Hoppman

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic

Rhett P. Ketterling

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic

Jess F. Peterson

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic

Patricia T. Greipp

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic

Linda B. Baughn

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic